Pure Nicotinamide Mononucleotide Powder Anti Aging Supplement

Product Description

NMN-SGS TEST REPORT.PDF

Pure Nicotinamide Mononucleotide Powder Anti Aging Supplement

Product Introduction of Nicotinamide Mononucleotide Powder
Nicotinamide Mononucleotide Powder is an intermediate in the remedial synthesis pathway of nicotinamide adenine dinucleotide (NAD+) in mammals. In humans, Nicotinamide Mononucleotide Powder performs its physiological functions by converting to NAD+, such as activating NAD+ substrates Nicotinamide Mononucleotide Powder is used in the human body to perform physiological functions such as activating the NAD+ substrate dependent enzyme Sirt1 (histone deacetylase, also known as silencing regulatory protein), regulating cell survival and death, and maintaining redox status. Recent studies have found that by regulating the level of β-NMN in organisms, it can have a better therapeutic and restorative effect on cardiovascular diseases, neurodegenerative diseases and degenerative diseases of aging; in addition, β-NMN can also protect and repair the function of pancreatic islets, increase insulin secretion, and prevent and treat metabolic diseases such as diabetes and obesity by participating in and regulating the endocrine function of the body.

Certiicate of Analysis

Product Function of Nicotinamide Mononucleotide Powder
1. Therapeutic effect on stroke
Nicotinamide Mononucleotide Powder prevents ischaemia-induced neuronal apoptosis and promotes neural regeneration after ischaemia by improving bioenergetic metabolism in post-ischaemic tissues, thus NMN has a strong protective effect against ischaemic brain injury. For hemorrhagic brain injury, increasing the level of NMN can reduce the hemoglobin content in infarcted tissues, reduce hemorrhage and edema, and reduce the oxidative toxicity of brain tissue damage caused by oxidative stress.
2. Therapeutic effect on cardiac ischemia-reperfusion
Exogenous Nicotinamide Mononucleotide Powder increased the NAD+ and NADH content in the heart and reduced the infarct size after ischemia.
3. Therapeutic effects on Alzheimer's disease
Nicotinamide Mononucleotide Powder improved behavioural cognitive impairment, inhibited β-amyloid production and reduced neurological amyloid plaque load, synaptic damage and inflammatory response in mice with Alzheimer's disease by activating c-Jun amino-terminal kinase.
4. Therapeutic effects on Parkinson's disease
NMN increased neuronal cell survival, reduced apoptosis, restored NAD+ and ATP levels, inhibited apoptosis, counteracted energy damage and improved mitochondrial inhibitor-induced impairment of energy metabolism.

5. Aging retardation
Studies have found that Nicotinamide Mononucleotide Powder supplementation accelerates the turnover of remedial biosynthesis of NAD+, thereby activating the Sirt1 response, which induces DNA silencing and contributes to anti-ageing and lifespan extension.
6. Therapeutic effects on type 2 diabetes
Nicotinamide Mononucleotide Powder was found to improve islet dysfunction, reverse pro-inflammatory cytokine-mediated changes in the expression of genes encoding islet markers, reduce the expression of pro-inflammatory factors, restore insulin secretion and improve cytokine-mediated islet dysfunction in the high fructose group of mice.
7. Therapeutic effects on acute kidney injury
Studies have shown that Sirt1 and NAD+ levels decrease with age; reduced NAD+ and Sirt1 in the kidneys of aged organisms leads to increased susceptibility to AKI; supplementation with NMN protects mice from cisplatin (which can be used to inhibit DNA replication) induced AKI; the mechanism of NAD+/Sirt1 renoprotection involves epigenetic regulation of the JNK pathway.

8. Therapeutic effects on vascular disorders
Nicotinamide Mononucleotide Powder supplementation reduces collagen accumulation throughout the vasculature, increases arterial elastin accumulation, reduces atherosclerosis, and delays arterial aging with age. In addition, NMN Beta Nicotinamide can improve plasma lipid distribution and maintain blood glucose levels, thereby improving vascular function.
9. Therapeutic effects on degenerative diseases of vision
Supplementation with Nicotinamide Mononucleotide Powder restores normal basal glycolytic function, mitochondrial function and the ability to adapt to metabolic stress in mice, reduces photoreceptor cell death, and significantly improves dark vision and retinal function.
10. Therapeutic effects on obesity-related diseases
Exercise is an effective tool in the fight against obesity because it increases NAD+ levels and enhances mitochondrial energy metabolism, while Nicotinamide Mononucleotide Powder can also increase NAD+ levels. A study comparing the effects of NMN Beta Nicotinamide supplementation and exercise on the fight against obesity showed that NMN Pure Powder supplementation increased lipolysis and increased NAD+ levels in the liver, while exercise increased NAD+ levels mainly in the muscle, suggesting that NMN Pure Powder, a NAD+ precursor based on NMN, could be used to treat This suggests the possibility of using NMN Pure Powder as a NAD+ precursor for the treatment of obesity-related liver diseases such as non-alcoholic fatty liver disease.