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β-Nicotinamide Mononucleotide Pure NMN Powder Supplemental Nutrition

Minimum Order Quantity : 1kg, 25kg/drum, sample is available Price : Negotiable
Packaging Details : Vacuum Aluminum Foil Bag; Fiber Drum for 25kg with inside double layer food grade poly bag Delivery Time : 5-7 working days
Payment Terms : T/T, Western Union, Pay Pal, Alibaba Assurance Account Supply Ability : 250kg/month
Place of Origin: China Brand Name: Xi'an Le-Nutra
Certification: FDA,ISO9001,HACCP,HALAL,KOSHER etc Model Number: Pure NMN Powder

Detail Information

Product Name: Beta Nicotinamide Mononucleotide CAS: 1094-61-7
Molecular Formula: C11H15N2O8P Molecular Weight: 334.22
Mainly Used: Forebody Of NAD+, Anti Aging Application: Food Supplements; Pharmaceutical Use; Cosmetic
Grade: Food Grade, Pharmaceutical Grade Appearance: White Powder
High Light:

Nicotinamide Mononucleotide Pure NMN Powder


Pure NMN Powder Supplemental Nutrition


Β Nicotinamide Mononucleotide Supplemental Nutrition

Product Description


β-Nicotinamide Mononucleotide Pure NMN Powder Supplemental Nutrition

Product Introduction of β-Nicotinamide Mononucleotide
β-Nicotinamide Mononucleotide is one of the intrinsic substances in the human body and plays an important role in the energy production of human cells. It is involved in the synthesis of intracellular NAD (nicotinamide adenine dinucleotide, an important coenzyme in cellular energy transformation) and plays a key role in cellular energy metabolism. Nicotinamide Mononucleotide is currently being tested in human clinical trials for its anti-ageing effects and safety. Studies have also shown that β-Nicotinamide Mononucleotide can also play a regulatory role in insulin secretion and has an effect on mRNA expression levels, so it has a wide range of applications in the field of medical therapy.

β-Nicotinamide Mononucleotide Pure NMN Powder Supplemental Nutrition 0


β-Nicotinamide Mononucleotide Distribution in Organs
The synthases and depleting enzymes of β-Nicotinamide Mononucleotide are also tissue specific: NMN is widely distributed throughout the body in tissues and organs and is present in a wide range of cells from embryonic development onwards. Little is known about the metabolism and biodistribution of NAD+ precursors in various tissues and cells, in contrast to the expression of the NMN synthases NAMPT and NRKs, and the NMN depleting enzymes NMNATs.
NAMPT is ubiquitous in vivo, but there are large differences in expression levels between tissues. In brain and heart, it's dependent remediation pathway is the preferred mode of NAD+ production; whereas in skeletal muscle, the NRK-dependent remediation pathway is the preferred mode of NAD+ production.
2. NMNATs(NMN Enzyme consumption)
The metabolic profile of mouse tissues showed that the activity of NMNAT isoforms was much higher than that of NAMPT, and the activity of NMNAT isoforms was unrestricted in most tissues, except for blood.
3. NRKs
Expression analysis of NRK isoforms suggests that NRK1 is ubiquitous, whereas NRK2 is predominantly found in skeletal muscle. Consistent with this, chronic NR supplementation caused increased NAD+ levels in muscle, but little effect in brain or white adipose tissue.

Certiicate of Analysis

Product Name: β- Nicotinamide Mononucleotide ( β-NMN) Country of Origin: China
Molecular Formula: C11H15N2O8P CAS No: 1094-61-7
Batch Number: LEN-20220301 Manufacture Date: Mar 1st, 2022
Quantity 220KGS Expiry Date: Feb 28th,2024


Appearance Pure White fine particle Complies Organoleptic
Odor Characteristic Complies Organoleptic
Clarity( 1g/ 100ml water) Rapid solubility to produce crystal clear, colorless liquid Complies Organoleptic
Particle Size 100% pass 40 Mesh sieve Complies CP2020
Bulk Density Report data 0.33g/ml GB18798.5
Tap Density Report data 0.45g/ml GB18798.5
Purity (area%) ≥99.0 99.90% HPLC

β - nicotinamide

mononucleotide( w/ w% )

≥99.0 99.50% HPLC
Total Impurities ≤ 0.4 0.10% HPLC
Loss on drying(%) ≤ 1.0 0.30 GB5009.3
PH( 1mg/ 1ml water) 2.0-4.0 3.1 GB9724
Heavy metals
Heavy Metals(ppm) ≤ 10 <10 CP2020
Arsenic(ppm) ≤0.5 Complies CP2020
Mercury(ppm) ≤0. 1 Complies CP2020
Lead(ppm) ≤0.5 Complies CP2020
Cadmium(ppm) ≤0. 1 Complies CP2020
Residual solvent

Residual solvent Methanol(ppm)




Ethanol(ppm) ≤5000 65 GC
Ethyl acetate(ppm) ≤5000 N.D GC


phosphate( ppm)

≤400 N.D GC
Total Plate Count(cfu/g) ≤1000 <10 CP2020
Yeast & Mold(cfu/g) ≤100 <10 CP2020
Coliform(MPN/g) ≤3 N.D CP2020
E.Coli (/10g) Negative Negative CP2020
Salmonella(/25g) Negative Negative CP2020
Storage Store in a well- closed container away from moisture, light and oxygen.


How does β-Nicotinamide Mononucleotide enter your cells?
β-Nicotinamide Mononucleotide has membrane transporters on the surface of some cells that directly translocate NMN into the cell, so β-Nicotinamide Mononucleotide has two modes of entry into the cell.

β-Nicotinamide Mononucleotide Pure NMN Powder Supplemental Nutrition 1

1. Direct entry into cells via transporters: In early 2019, the idea was confirmed by a paper in nature metabolism, which found the presence of an NMN-specific transporter in the mouse small intestine called Slc12a8, an amino acid and polyamine transporter that is highly selective for NMN and does not transport NaMN, which is structurally very similar to NMN.
2. Enters the cell via dephosphorylation of CD73 on the cell membrane surface to NR (via the equilibrium nucleoside transporter protein ENTs), which is subsequently catalyzed by the cytoplasmic NRK enzyme to NMN and is utilized in the mitochondria (no NRK in mitochondria).
NAM is both a precursor to NMN and a product of NAD+ hydrolysis by the NADase activity depletion pathway CD38. Thus the synthesis, utilisation and regeneration of NAD+ is an cycle involving the intracellular and extracellular.NMN/NR→NAD+→NAM→NMN


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