High Purity Beta Nicotinamide Mononucleotide Powder CAS 1094-61-7

Product Description

NMN-SGS TEST REPORT.PDF
High Purity Beta Nicotinamide Mononucleotide Powder CAS 1094-61-7
Product Introduction of Beta Nicotinamide Mononucleotide
Beta Nicotinamide Mononucleotide is a synthetic substrate for Coenzyme I. Also NMN has been used in anti-ageing studies. A collaboration between Keio University in Japan and the University of Washington in the USA is conducting human clinical trials on the anti-ageing effects and safety of beta-NMN. Studies have shown that beta-NMN can also have a regulatory effect on insulin secretion and an effect on mRNA expression levels. beta-NMN has a wide range of applications in the field of medical therapy.
Beta Nicotinamide Mononucleotide A product of the extracellular nicotinamide phosphoribosyltransferase (eNAMPT) reaction and a key NAD+ intermediate. It improves glucose tolerance by restoring NAD+ levels in HFD-induced T2D mice. It also enhances hepatic insulin sensitivity and restores gene expression associated with oxidative stress, inflammatory responses and circadian rhythms, in part through SIRT1 activation.
It is inherent in the human body and is also abundant in some fruits and vegetables, including broccoli and cabbage.

Product Function of Beta Nicotinamide Mononucleotide
Beta Nicotinamide Mononucleotide is a direct way to supplement NAD+. It is by significantly enhancing the ability to repair DNA damage in cells that nicotinamide mononucleotide ultimately reverses the effects of ageing. Nicotinamide mononucleotide is converted into "nicotinamide adenine dinucleotide (NAD)", a substance essential for energy metabolism in the body. In mice, it has been shown to activate a gene in the body called acetylase, which has the effect of prolonging life and treating diabetes, etc. NAD is a substance that can be produced by the body and studies have shown that the amount of NAD in the body decreases with age.
 
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Anti-ageing Mechanisms of Beta Nicotinamide Mononucleotide
Beta Nicotinamide Mononucleotide is a precursor substance for NAD+, a cofactor of longevity proteins in the human body. NAD+ is an important coenzyme in the tricarboxylic acid cycle, promoting the metabolism of sugars, fats and amino acids and participating in energy synthesis; it is also the only substrate for coenzyme I depleting enzymes (the only substrate for the DNA repair enzyme PARP, the only substrate for longevity proteins, and the only substrate for cyclic ADP ribose synthase CD38/157). NAD+ is involved in all aspects of human metabolism and is a key coenzyme, without which metabolism will not work, and in the elderly, lack of NAD+ will lead to all kinds of major and minor problems.