Product Description
Product Introduction of API Powder
Reduced glutathione (GSH) is an important intracellular substance, consisting of glutamic acid, cysteine and glycine, containing sulfhydryl groups, which plays an important role in maintaining the biological functions of cells, and has a variety of biochemical functions, including participating in the tricarboxylic acid cycle and sugar metabolism, being a coenzyme of glyceraldehyde phosphate dehydrogenase and propyl phosphate dehydrogenase, activating a variety of enzymes, promoting sugar, fat and protein metabolism, and influencing the metabolic process of cells. GSH can combine with pro-Chemicalbook hepatotoxic substances to protect the synthesis, detoxification and inactivation of hormones in the liver and promote the metabolism of bile acids. It facilitates the absorption of fats and fat-soluble vitamins in the digestive tract. It is suitable for reducing the toxic effects of chemotherapy and radiotherapy, especially in high doses; or for the treatment of various hypoxaemia, such as acute anaemia, acute respiratory distress syndrome, sepsis, etc.; it can be used in the treatment of liver diseases, including viral, drug, ethanol and other chemical toxicity-induced liver damage. It is also used as an adjunct to the treatment of organophosphorus, amino or nitroaromatic compound poisoning. It is also useful in the treatment of acute drug-related kidney injury, uremia, diabetic complications and neuropathy.
Certificate of Analysis
| Test ltems |
Speciflcations |
Results |
| Appearance |
White or almost white crystallin powder |
White crystalline powder |
| ldentification IR |
Conforms to the Reference Spectrum |
Confoms to the Reference
Spectrum
|
| Optical rotation |
15.5°to-17.5° |
-16° |
| Appearance of solution |
Clear and colorless |
Clear and colorless |
| Chlorides |
≤ 200 ppm |
Complied |
| Sulfates |
≤ 300 ppm |
Complied |
| Ammonium |
≤ 200 ppm |
Complied |
| ron |
≤ 10 ppm |
Complied |
| Arsenic |
≤ 1ppm |
Complied |
| Heavy metals |
≤ 10 ppm |
Complied |
| Cadmium (Cd) |
≤ 1 ppm |
Complied |
| Plumbum (Pb) |
≤ 3 ppm |
Complied |
| Mercury (Hg) |
≤ 1 ppm |
Complied |
| Sulfated ash |
≤ 0.1% |
0.073% |
| Loss on dying |
≤ 0.5% |
0.330% |
| Bulk densily |
≥ 0.2g/ml |
0.3213g/ml |
| Tapped density |
≥ 0.4g/ml |
0.5155g/ml |
| Total plate count |
≤1000cfu/g |
Complied |
| Yeast and mold count |
≤100cfu/g |
Complied |
| Salmonella Negative |
Negative |
Complied |
| Related Substances |
Total |
Maximum 2.0% / 1.58% |
| GSSG |
Maximum 1.5% / 10.57% |
| Assay |
98.0% to 101.0% |
98.32% |
Use of API Powder
1. Reduced glutathione is a small molecule peptide, which exists in large quantities in living organisms, especially in liver cells, and has the function of protecting liver cell membranes, promoting liver enzyme activity, and acting as a detoxification agent in combination with many toxic chemicals. It is very effective in treating liver injury and cirrhosis of the liver caused by various reasons such as drug poisoning and alcoholism.
2. It has the functions of antioxidant, free radical scavenging, detoxification, immunity enhancement, delaying aging, anti-cancer and anti-radiation hazard.
3. Biochemical reagents, antidotes, mainly for poisoning by heavy metals, acrylonitrile, fluoride, carbon monoxide and organic solvents
4. Biochemical research
5. Endogenous antioxidants that play an important role in the reduction of reactive oxygen species formed during cellular metabolism and burst respiration. Glutathione-S-transferase catalyses the formation of glutathione thioethers with xenobiotics, leukotrienes and other molecules with electrophilic centres. Glutathione also forms disulphide bonds with cysteine residues in proteins. Through these mechanisms, it can have the curious effect of reducing the effectiveness of anti-cancer agents.
Application of of API Powder
1. Food additives
2. Antidote
3. Anti-allergic agents
4. Liver protector
5 .Antioxidants
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