CAS 13190-97-1 API Powder Solanesol For Synthesizing CoQ10 Vitamin K2

Product Description

API Powder Solanesol CAS 13190-97-1 For Synthesizing CoQ10 Vitamin K2
Product Introduction of Solanesol
Solanesol is a natural product widely found in higher plants, mammals and microorganisms. It is a waxy white solid with a melting point of 33-42.5°C, insoluble in water and soluble in a variety of organic solvents. It was first isolated from plants by R.L. Rowland et al. in 1956, and in I959 Frickson et al. demonstrated by NMR spectroscopy that Solanesol was composed of nine isoprene units as tri-semi-terphenyl alcohols, and was later found to be present in tobacco leaves at a high content of about 0.3-0.5%. The Solanesol is now generally extracted from waste tobacco leaves as a raw material, first as a crude product (containing 17% lycopene), then as a fine product (70-75%) and then as a pure product (90%), which is then used mainly for the synthesis of Coenzyme Ql0 and Vitamin K2.

Product Function and Application of Solanesol
High purity Solanesol is a key intermediate in the synthesis of best-selling APIs such as CoQ10 and vitamin K2. Western medical researchers have found that high purity Solanesol can be used directly as a clinical drug in its own right, with the main clinical applications being anti-heart failure, treatment of liver damage and adjuvant therapy for cancer. According to the Indian Medical Journal, a number of hospitals in India are already conducting controlled clinical trials of high purity Solanesol preparations as a diabetes treatment agent and an anti-cancer drug. Once these new applications have been accepted by the medical community, the total sales of high-purity Solanesol in the international market will be greatly boosted in the future.

CoQ10, synthesised using Solanesol, promotes oxidative phosphorylation and synthesis of adenosine triphosphate (ATP), acts as an activator of cellular metabolism and respiration, helps to enhance the function of the human immune system, etc. To date, CoQ10 has been included in the pharmacopoeias of the United States, Europe and Japan. In recent years, American pharmaceutical researchers have also found that CoQ10, when used in combination with statin lipid-lowering drugs, can greatly reduce side effects such as rhabdomyolysis and prevent acute myocardial infarction in coronary heart patients. It is worth noting that, in a world of drug safety incidents, there have been no reports of CoQ10's toxic side effects.

Other Information of Solanesol
The two most common processes used to produce CoQ10 are synthetic (where the main raw material is high purity Solanesol) and microbial fermentation. Japan is one of the few countries in the world that first mastered these two CoQ10 production processes and is also the main exporter of CoQ10 in the world. According to statistics, the amount of CoQ10 exported from Japan once accounted for about 90% of the total CoQ10 sales in the international market. However, the main raw material for the synthesis of CoQ10, high purity lycopene, was previously produced in Japan, but as China and India became more capable of producing crude lycopene in large quantities, Japan switched to importing crude lycopene from China and India to synthesise CoQ10 with improved purity and then export it to the European and American markets. With the development of China, it is now possible to save more money by importing both lycopene and CoQ10 from China.