Insoluble Water Sulphonamide Antibiotic API Powder CAS NO 72-14-0

Product Description

Product Description of API Powder

sulfathiazole API is white or light yellow crystalline particles or powder, odorless or almost odorless. When encountering light, the color gradually becomes darker. Slightly soluble in ethanol, very slightly soluble in water, easily soluble in sodium hydroxide test solution, and soluble in dilute hydrochloric acid. Indications are used for pneumonia, hemorrhagic sepsis, and endometritis caused by animal sensitive bacteria. Pharmacology This product has the same antibacterial spectrum and action mechanism as sulfadiazine, but its antibacterial effect is slightly stronger than that of sulfadiazine.

COA

Biochemical Mechanism of API Powder

Sulfathiazole Powder is a Sulphonamide antibiotic that blocks the synthesis of dihydrofolate by inhibiting dihydrofolate synthase. Antibiotics.

Mode of action: Inhibition of folic acid synthesis in prokaryotes.

Antimicrobial spectrum: Gram-positive bacteria, Gram-negative bacteria, Chlamydia Mechanism of resistance: alteration of dihydrofolate synthase or alternative pathways of folate synthesis.

Usage of API Powder

Sulfathiazole CAS 72-14-0 is an organic sulfur compound that has been used as a short-acting sulfa drug. Objective: The degradation of 20 μg/L antimicrobial sulfathiazole in one of two batch reactors containing different waste water substrates began at 31st to 38th day. In the nitrification process (S3), the degradation rate of sulfathiazoles was significantly faster than that of sulfamethoxazole or sulfametriazine. The recovery of sulfathiazole was 64% at pH 9. Sulfathiazole has a ph constant of 7.1 and a retention time (tR) of 7.8. The S/N value of sulfathiazole exceeds 100 at 1 mg/kg level. The adsorption of sulfathiazole on inorganic adsorbent was pH dependent, which was consistent with sorbate morphology and charge characteristics of sorbate. The adsorption of sulfathiazole cations on clay minerals is the most important, followed by neutral substances .