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CAS 33818-15-4 Pharmaceutical Grade Api Powder Citicoline Sodium Odorless

Minimum Order Quantity : 1kg, 25kg/drum, sample is available Packaging Details : Vacuum Aluminum Foil Bag; Fiber Drum for 25kg with inside double layer food grade poly bag
Delivery Time : 5-7 working days Payment Terms : T/T, Western Union, Pay Pal, Alibaba Assurance Account
Place of Origin: China Brand Name: Xi'an Le-Nutra
Certification: FDA,ISO9001,HACCP,HALAL,KOSHER etc

Detail Information

Grade: Pharmaceutical Grade CAS No.: 33818-15-4
Citicoline Sodium: ≥98% Appearance: White Crystals Or Crytalline Powder, Odorless
Molecular Formula: C14H25N4NaO11P2 USE: After Injection Of Sodium Cytophosphatidylcholine Injection, It Can Rapidly Enter The Blood, And Some Of It Can Enter The Brain Tissue Through The Blood-brain Barrier. The Choline Part Becomes A Good Methylation Donor In The Body And Can Have Transmethylat
High Light:

CAS 33818-15-4 Api Powder


Odorless Citicoline Sodium Api Powder


White Citicoline Sodium Api Powder

Product Description

Procuct Introduction of API Powder

Citicoline is a major component of cell membrane phospholipids and is a complex organic molecule composed of ribose, pyrophosphate, cytosine and choline. citicoline is water soluble and its oral bioavailability is >90%. citicoline has no mitogenic or chemotactic effect on hCMEC/D3. However, it significantly enhances wound healing Chemicalbook, spheroid germination and strongly induces the formation of endothelial tubular structures in the basement membrane matrix. citicoline induces the expression of phosphorylated ERK1/2. It protects hCMEC/D3 from cell injury/apoptosis. citicoline induces angiogenesis and improves survival of human brain microvascular endothelial cells through p-ERK1/2 and IRS-1 related pathways.

Bioactivity​ of API Powder

Citicoline (CDP-choline) is an essential intermediate in the synthesis of lecithin, the main phospholipid of cell membranes. It increases plasma adrenocorticotropic hormone levels and enhances serum thyrotropin levels.

In vitro studies.

CAS 33818-15-4 Pharmaceutical Grade Api Powder Citicoline Sodium Odorless 0

Certificate of Analysis

Product Name Citicoline Sodium
CAS No. 33818-15-4
Analysis Standard ChP 2020 Part II
Grade Pharmaceutical grade
Item Standard Test Result
Citicoline Sodium ≥98% 100.2%
Appearance White crystals or crystalline powder, odorless Complies
Ammonium ≤0.05% Complies
Phosphate ≤0.1% Complies
Iron ≤0.01% Complies
Chloride ≤0.05% Complies
PH 6.0-7.5 6.6
Solubility Soluble in water, insoluble in ethanol, insoluble in acetone  
Loss on Drying ≤6% 1.6%
Heavy Metal ≤5ppm Complies
Arsenic ≤0.0001% Complies
Related substance
5’-CMP ≤0.3% 0.023%
Other single impurity ≤0.2%  
Other total impurities ≤0.7% 0.011%
Residual solvents
Methanol ≤0.3% Not detected
Ethanol ≤0.5% 0.003%
Acetone ≤0.5% Not detected
Bacterial endotoxins <0.3EU/mg Complies

Drugs for the central nervous system (API Powder)

Coenzyme. For acute craniocerebral trauma and post-brain surgery disorders of consciousness. Acute craniocerebral trauma and post-brain surgery disorders of consciousness, for hemiplegia due to stroke can gradually restore the function of the Chemicalbook extremities, also for other acute injuries to the central nervous system caused by functional and consciousness disorders, also for ischaemic cerebrovascular disease and vascular dementia.

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