CDPC Citicoline Sodium 98% API Pharmaceutical Powder Nucleic Acid Derivative

Minimum Order Quantity :	1kg, 25kg/drum, sample is available	Packaging Details :	Vacuum Aluminum Foil Bag; Fiber Drum for 25kg with inside double layer food grade poly bag
Delivery Time :	5-7 working days	Payment Terms :	T/T, Western Union, Pay Pal, Alibaba Assurance Account

Place of Origin:	China	Brand Name:	Xi'an Le-Nutra
Certification:	FDA,ISO9001,HACCP,HALAL,KOSHER etc

Detail Information
CAS No.:	33818-15-4	Grade:	Pharmaceutical Grade
Citicoline Sodium:	≥98%	Appearance:	White Crystals Or Crytalline Powder, Odorless
Solubility:	Soluble In Water, Insoluble In Ethanol, Insoluble In Acetone	Molecular Formula:	C14H25N4NaO11P2
Molecular Weight:	512.32	Effect:	It Enhances The Function Of The Upstream Reticular Activation System Of The Brainstem, Strengthens The Function Of The Vertebral System And Improves Motor Paralysis, So It Has A Certain Effect On Promoting The Recovery Of Brain Function And Promoting Awake
High Light:	98% API Pharmaceutical Powder , CDPC Citicoline Sodium Pharmaceutical Powder , Nucleic Acid Pharmaceutical Powder

Product Description

Product Information of API Powder

Sodium cytophosphatidylcholine is a nucleic acid derivative. it was discovered by Geiger in 1956 that it could restore brain damage in animal tests; in 1957, Kennedy's research confirmed its significance in cerebral phospholipid synthesis. in 1961, it was developed and manufactured by Takeda Pharmaceuticals in Japan and registered in China in 1988. It is presently the best-selling drug clinically used to treat brain disorders and is instrumental in the synthesis of lecithin, which improves brain function by promoting the synthesis of lecithin. It is proven that cytarabine can increase the level of norepinephrine and dopamine in the central nervous system, thus treating cerebrovascular disease, traumatic brain injury and cognitive impairment from various causes of chemical books without significant side effects.

CDPC Citicoline Sodium 98% API Pharmaceutical Powder Nucleic Acid Derivative 0

Certificate of Analysis

Product Name	Citicoline Sodium
CAS No.	33818-15-4
Analysis Standard	ChP 2020 Part II
Grade	Pharmaceutical grade

Item	Standard	Test Result
Citicoline Sodium	≥98%	100.2%
Appearance	White crystals or crystalline powder, odorless	Complies
Ammonium	≤0.05%	Complies
Phosphate	≤0.1%	Complies
Iron	≤0.01%	Complies
Chloride	≤0.05%	Complies
PH	6.0-7.5	6.6
Solubility	Soluble in water, insoluble in ethanol, insoluble in acetone
Loss on Drying	≤6%	1.6%
Heavy Metal	≤5ppm	Complies
Arsenic	≤0.0001%	Complies
Related substance
5’-CMP	≤0.3%	0.023%
Other single impurity	≤0.2%
Other total impurities	≤0.7%	0.011%
Residual solvents
Methanol	≤0.3%	Not detected
Ethanol	≤0.5%	0.003%
Acetone	≤0.5%	Not detected
Bacterial endotoxins	<0.3EU/mg	Complies

Pharmacological Effects of API Powder

Citicoline Sodium strengthens the brainstem reticular formation, particularly activating systems in the superior reticular formation, which is closely related to consciousness, potentiates the action of the pyramidal system, and inhibits the action of the of the extrastriate system to encourage arousal. It can also decrease cerebrovascular resistance, and increase the perfusion of cerebral blood flow and stimulate the metabolism of brain substances. It is used primarily to treat neurological sequelae caused by craniocerebral injuries and cerebrovascular accidents, and can be used to treat Parkinson's syndrome and has certain efficacy in Alzheimer's disease; it is used to treat cerebrovascular and cardiovascular diseases; others such as delaying aging and improving learning effectiveness and memory also have certain efficacy.

Cytidine 5'-bis-choline phosphate (CDP-choline), which supports the synthesis of lecithin, is produced in choline-phosphate cytidylyltransferase EC 2.7.7.15; used to study its role in neurorehabilitation.

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