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123171-59-5 Cefepime Hydrochloride Powder C19H28Cl2N6O6S2

Price : $260.00 - $319.00/Kilograms Packaging Details : 25kgs packaging Fiber drum outside and plastic bag inside 1-25kgs packaging aluminium bag<br>outside and double plastic bag inside.
Place of Origin: Shaanxi, China Brand Name: Le-nutra
Model Number: Le-nutra

Detail Information

CAS No.: 123171-59-5 Other Names: Cefepime Dihydrochloride Monohydrate
MF: C19H28Cl2N6O6S2 EINECS No.: /
Type: Animal Pharmaceuticals Grade Standard: Medicine Grade
Usage: Animal Pharmaceuticals Purity: 99%, 99%
English Name: Cefepime Hydrochloride Powder Appearance: White Powder
Test Method: HPLC Grade: Phamaceutical Grade
Molecular Formula: C19H28Cl2N6O6S2 MOQ: 1KG
CAS: 123171-59-5 Odor: Characteristic
Shelf Life: 2 Years Port: Tianjin/Shanghai/Qingdao
High Light:

123171-59-5 Cefepime Hydrochloride

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Cefepime Hydrochloride C19H28Cl2N6O6S2

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123171-59-5 Hydrochloride Powder

Product Description

123171-59-5 Cefepime Hydrochloride Powder C19H28Cl2N6O6S2

English name
Cefepime Hydrochloride powder
Purity
99%
Appearance
White powder
Odor
Characteristic
CAS
123171-59-5
Test Method
HPLC 
 
Description
Cefepime hydrochloride
Cefepime hydrochloride is used to treat lower respiratory tract, urinary tract, skin and soft tissues, biliary tract, abdominal and pelvic cavity, gynecological and obstetric infections, and sepsis caused by sensitive bacteria. It is also used for empirical treatment of moderate and severe bacterial pneumonia.
 
Specification
Tests
Specifications
Result
Description
White powder
Meets the requirements
Identification
Meets the requirements
Meets the requirements
Water
3.0-4.%
3.2%
Crystallinity
Meets the requirements
Meets the requirements
Bacterial endotoxins
<0.04EU/mg
Meets the requirements
Residue on Ignition
≤0.1%
0.08%
Sterility
Meets the requirements
Meets the requirements
N-methylpyrrolidine
≤0.3%
Not detected
Heavy Metals
≤20ppm
<20ppm
Sterile
conform
complies
Related compounds
 
 
Cefepime related compound A
≤0.3%
Not detected
Cefepime related compound B
≤0.2%
Not detected
Any other impurity
≤0.1%
0.04
Assay
825~911ug/mg
856 ug/mg
Function and Application
123171-59-5 Cefepime Hydrochloride Powder C19H28Cl2N6O6S2 2
 
123171-59-5 Cefepime Hydrochloride Powder C19H28Cl2N6O6S2 3

Cefepime is indicated for the treatment of the following infections caused by susceptible bacteria:

1) Lower respiratory tract infections, such as pneumonia, bronchitis, etc. 2) Urinary system infections, such as pyelonephritis. 3) Skin and soft tissueinfections. 4) Intraperitoneal infections (including peritonitis and biliary infections, etc.). 5) Obstetrics and Gynecology infection. 6) Septicemia.

Pharmacological action

1. Cefepime hydrochloride is a fourth-generation cephalosporin whose antibacterial mechanism is to inhibit the synthesis and metabolism of bacterial cell wall by binding to one or more penicillin-binding proteins (PBPs) of bacterial cells, thereby exerting an antibacterial effect. Cefepime is characterized by high antibacterial activity, stable β-lactamase, especially chromosome-mediated Richmond-sykes type I β-lactamase, and very sensitive to Gram-negative bacilli producing type I β-lactamase Strong antibacterial activity. Cefepime has antibacterial activity against Enterobacter, Citrobacter and Serratia
producing type I β-lactamase over third-generation cephalosporins such as ceftazidime; antibacterial against Pseudomonas aeruginosa The effect is similar to or slightly worse than ceftazidime; the antibacterial activity against Gram-positive bacteria such as Staphylococcus aureus is also enhanced than that of the third-generation cephalosporin.
2. Gram-negative aerobic bacteria: Pseudomonas (including Pseudomonas aeruginosa, Pseudomonas putida), Escherichia coli, Klebsiella, Enterobacter (including Enterobacter cloacae, gas production) Enterobacter), variant bacillus (including Proteus mirabilis, common Proteus), citrate bacteria, Campylobacter jejuni, Haemophilus haemophilus, Haemophilus influenzae, Haemophilus parainfluenzae, Moraxella catarrhalis, gonorrhea Neisseria, Neisseria meningitidis, Salmonella, Serratia, Shigella, Yersinia enterocolitica.
3. Anaerobic bacteria: Bacteroides, Clostridium perfringens, Clostridium, Streptococcus pneumoniae, and Weirong cocci. Cefepime hydrochloride has no antibacterial activity against most enterococci (such as Enterococcus faecalis, methicillin-resistant Staphylococcus), Pseudomonas maltophilia, Bacteroides fragilis, and Clostridium difficile.
 

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