Smoke Tree Extract Fisetin Powder 96% CAS 528-48-3 Fustel

Product Description

Smoke Tree Extract Fisetin Powder 96% CAS 528-48-3 Fustel

Product Introduction of Smoke Tree Extract
Smoke Tree Extract, being a flavonoid with inherent antioxidant properties, not only has direct antioxidant activity, but also increases the levels of the main intracellular antioxidant glutathione. Even under oxidative stress, it maintains mitochondrial function very well and even the very fragile neuronal cells are well protected.
Smoke Tree Extract inhibits the NF-κB pro-inflammatory signalling pathway by activating β-catenin protein and silencing the expression of TLR4, thereby down-regulating the release of inflammatory cytokines and achieving an anti-inflammatory effect.

Plant source

Smoke Tree Extract is a flavonoid, and therefore a polyphenol, it is synthesised by the phenylpropanoid pathway in which phenylalanine, an amino acid, is first converted into 4-coumaroyl-CoA and then into the flavonoid biosynthesis pathway. The first enzyme in this pathway, Chalcone synthase, converts 4-coumaroyl-CoA into chalcone, and all flavonoids are made with a chalcone backbone, and these compounds made with a chalcone backbone are collectively known as chalcone analogues. Various enzymes, including isomerases and hydroxylases, have different effects on chalcones depending on the subset of products, and transferases regulate the solubility of flavonoids by catalyzing the addition of methyl groups or sugars, which allows the plant body to control random changes in physiological activity.

Certificate of Analysis

Manufacturing Process of Smoke Tree Extract

Product Function of Smoke Tree Extract
Smoke Tree Extract was found to be an effective anti-aging drug in wild-type mice, increasing lifespan, reducing tissue markers of ageing and slowing down ageing-related diseases; studies on cultured tissues of human umbilical vein endothelial cells, which produce ageing, showed that it promotes apoptosis by inhibiting the activity of the anti-apoptotic protein Bcl-xL. It has been shown to promote apoptosis by inhibiting the activity of the anti-apoptotic protein Bcl-xL. The potential of laccasein as an anti-aging agent is approximately twice that of quercetin.

Laboratory studies on cultured cells have shown that Smoke Tree Extract inhibits several cytokines that promote inflammation, including tumour necrosis factor-alpha, Interleukin 6 and NF-κB, among others. Laboratory studies have also shown that it up-regulates the activity of glutathione, an endogenous antioxidant, and that it itself is a reducing agent that reacts with reactive oxygen species to neutralise them. Like other flavonoids, it has a flat structure and multiple carbon rings, and Smoke Tree Extract has the ability to scavenge free radicals due to its electron-donating properties, which are due to the presence of two hydroxyl groups in one ring and one hydroxyl group in the other.