Anti Aging Cotinus Coggygria Fisetin Powder CAS 528-48-3
Phone Number : 86-15209233790
WhatsApp : +8615209233790
Minimum Order Quantity : | 1kg, 25kg/drum, sample is available | Price : | Negotiable |
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Packaging Details : | Vacuum Aluminum Foil Bag; Fiber Drum for 25kg with inside double layer food grade poly bag | Delivery Time : | 5-7 working days |
Payment Terms : | T/T, Western Union, Pay Pal, Alibaba Assurance Account | Supply Ability : | 500kg/month |
Place of Origin: | China | Brand Name: | Xi'an Le-Nutra |
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Certification: | FDA,ISO9001,HACCP,HALAL,KOSHER etc | Model Number: | Cotinus Coggygria Extract |
Detail Information |
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Product Name: | Cotinus Coggygria Extract | Appearance: | Yellow Needle Crystal |
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CAS: | 528-48-3 | Specification: | 50%, 80%, 85%, 96% |
Botanical Source: | Cotinus Coggygria Scop | Used Parts: | Twigs (peeled) |
Molecular Formula: | C15H10O6 | Solubility: | Soluble In Ethanol, Acetone And Acetic Acid. Practically Insoluble In Water, Ether, Benzene, Chloroform And Petroleum Ether |
Grade: | Pharmaceutical Grade, Food Grade | Mainly Use: | Anti-tumour, Inhibits Tumour Cells, Anti-depressant, Improves Immune Cell Activity, Improves Long-term Memory |
High Light: | Anti Tumor Bulk Fisetin Powder,80% Pure Bulk Fisetin Powder,Anti Tumor Cotinus Coggygria Extract |
Product Description
Pure Bulk Fisetin Powder Cotinus Coggygria Extract Anti Tumor
Product Introduction of Fisetin Powder
Fisetin Powder is a polymeric pharmaceutical ingredient. It is a yellow needle-like crystal with a melting point of 330°C (decomposition). It is soluble in ethanol, acetone and acetic acid. Almost insoluble in water, ether, benzene, chloroform and petroleum ether. From RhussuccedaneaL, Cotinus coggygria, etc. of the lacquer family. It inhibits the production of prostaglandin in the fibroblasts of 3T3 mice with an ID50 of 42.0 U.M. It inhibits allose reductase in the rat eye lens with an ID50 of 10-6 M. In mouse small intestine specimens, its antispasmodic effect against acetylcholine was 166% of that of poppy bases. A team of Japanese and American researchers found in animal studies that Fisetin Powder in vegetables and fruits helped to improve memory.
Product Function of Fisetin Powder
1. Prostaglandin inhibition: Inhibits the production of prostaglandin in fibroblasts from methylcholanthrene transmutated 3T3 mice at an effective inhibitory concentration (ID50) of 42.0 UM.
2. Enzyme Inhibition: Inhibits allose reductase in the rat eye lens at an ID50 of 10-6M
3. Antispasmodic: In mouse small intestine specimens, the antispasmodic effect of acetylcholine was 166% of that of poppy bases.
4. A team of Japanese and American researchers found in animal studies that laccasein in vegetables and fruits helps to improve memory.
Fisetin Powder is of increasing interest because it can exert anti-tumour effects by inhibiting tumour cell proliferation and signal transduction pathways and inducing apoptosis in tumour cells. Compared to the API, low doses of liposomes can significantly increase the antitumour effect; preparation of laccasein micelles can increase its solubility and antitumour effect.
Certificate of Analysis
ITEM | SPECIFICATION | METHOD | RESULTS |
Physical Data | |||
Appearance | Fine Powder | Organoleptic | Conform |
Color | Yellow | Organoleptic | Conform |
Odor & taste | Characteristic | Organoleptic | Conform |
Analytical Quality | |||
Identification | Identical to R.S. Sample | HPLC | Conform |
Sieve analysis | 100% through 80 mesh | US Screen | Conform |
Fisetin | ≥98.0% | HPLC |
98.73% (Area normalisation method) |
Loss on Drying | ≤2.0% | 5g/100℃/2.5hrs | 0.64% |
Residual on ignition | ≤1.0% | 2g/535℃/3hrs | 0.79% |
Heavy metals | |||
Lead(Pb) | ≤2.0 ppm | Atomic Absorption | Conform |
Arsenic(As) | ≤2.0 ppm | Atomic Absorption | Conform |
Cadmium(Cd) | ≤1.0 ppm | Atomic Absorption | Conform |
Mercury(Hg) | ≤0.5 ppm | Atomic Absorption | Conform |
Microbiology | |||
Total Plate Count | ≤1000cfu/g | CP2015 | Conform |
Yeast & Mold | ≤100cfu/g | CP2015 | Conform |
E.Coli | Negative | CP2015 | Negative |
Salmonella | Negative | CP2015 | Negative |
AflatoxinB1 | ≤5.0ppb | CP2015 | Conform |
General Status | |||
Irradiation | Non-Irradiation | ||
GMO/BSE Status | No Genetically modified organism, Free of BSE | ||
Storage | Store in a well-closed container away from moisture, light and oxygen. |
Product Application of Fisetin Powder
Fisetin Powder has antioxidant, anti-inflammatory and neuroprotective pharmacological characteristics and can exert anti-tumour effects by inducing apoptosis, affecting the signal transduction pathways of tumour cells, inhibiting the proliferation of tumour cells, inhibiting the migration and invasion of tumour cells, etc. Studies have shown that Fisetin Powder can also exert antitumour effects by inhibiting the monoamine oxidase of the 5-hydroxytryptamine and norepinephrine systems. Fisetin Powder has also been shown to exert antidepressant effects by inhibiting the monoamine oxidase enzymes of the 5-hydroxytryptamine and norepinephrine systems. The Proceedings of the National Academy of Sciences reported that it stimulates signalling pathways and improves long-term memory; it also inhibits aflatoxin cytotoxicity. There are more related products on the market, such as the lacrimene capsules (30mg) produced by Doctor's Best in the USA, and Swanson Ultra's product lacrimene capsules (100mg) are some of the better selling health products containing lacrimene.
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