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Cas No 643 12 9 D Chiro Inositol Powder For Food Supplement Products

Minimum Order Quantity : 1kg, 25kg/drum, sample is available Price : Negotiable
Packaging Details : Vacuum Aluminum Foil Bag; Fiber Drum for 25kg with inside double layer food grade poly bag Delivery Time : 5-7 working days
Payment Terms : T/T, Western Union, Pay Pal, Alibaba Assurance Account Supply Ability : 1000kg/month
Place of Origin: China Brand Name: Xi'an Le-Nutra
Certification: FDA,ISO9001,HACCP,HALAL,KOSHER etc Model Number: D Chiro Inositol

Detail Information

Appearance: White Powder CAS NO: 643-12-9
Other Name: Chiro Inositol; DCI Specification: 99%
Solubility: Soluble In Water Function: Insulin Receptor Sensitiser, Treatment For PCOS,
Mainly Used In: Pharmaceutical, Food Supplements Grade: Food Grade
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Product Description

D Chiro Inositol Powder For Food Supplement Products High Quality
Myo Inositol & DCI Inositol
Myo-inositol is the most common form of the nine inositol isomers and has been shown in many clinical trials to play an important role in maintaining normal ovarian physiology. d-chiral inositol is another common inositol isomer and although there are also clinical trials supporting the effectiveness of d-chiral inositol, there is still controversy as to which dose is appropriate for which groups.

Differential isomerase converts Myo-inositol to D-chiral inositol, and the activity of differential isomerase varies considerably in different tissues and organs, resulting in a highly variable ratio of the two inositols in different tissues and organs. For example, the ratio of Myo-inositol to D-chiral inositol is 40:1 in peripheral blood, 20:1 in follicular membrane cells, and 70:1 to 100:1 in the follicular fluid of the dominant follicle.

Cas No 643 12 9 D Chiro Inositol Powder For Food Supplement Products 0

Certificates of Analysis

ITEM SPECIFICATION RESULT Test Method
Appearance White or off-white powder Complies Visual
Identification Meet requirements Complies HPLC
Solubility Soluble in water Complies Visual
Loss on drying ≤2.0% 0.9% 2g/105℃/5hrs
Residue on ignition ≤0.5% 0.01% 2g/600℃/4hrs
Chloride ≤0.5% Complies CP2015
Sulfate ≤0.5% Complies CP2015
Optical activity +63-67°,c=1.0 in H2O +64.22° AMN22
Melting point 220~238℃ 225~229℃ Melting point meter
Related compounds
Total impurities ≤2.0% 0.2% HPLC
Sucrose ≤1.0% Not detected HPLC
Pinitol ≤1.0% Not detected HPLC
Glucose (dextrose) ≤1.0% Not detected HPLC
Fructose ≤1.0% Not detected HPLC
Myo-Inositol ≤1.0% Not detected HPLC
Any unknow impurity ≤0.1% Complies HPLC
Total Heavy metals ≤10ppm Complies Atomic Absorption
Pb ≤2ppm Complies Atomic Absorption
As ≤2ppm Complies Atomic Absorption
Cd ≤1ppm Complies Atomic Absorption
Hg ≤0.1ppm Complies Atomic Absorption
Total microbacterial count ≤1000CFU/g Complies CP2015
Yeast &Mould ≤100CFU/g Complies CP2015
Escherichia Coli presence Negative Negative CP2015
Salmonella Negative Negative CP2015
S. Aureus Negative Negative CP2015
P. Aeruginosa Negative Negative CP2015
Assay ≥98% 99.4% HPLC
Conclusion The results conforms with the enterprise standard

 

Which one should we choose?
Myo inositol is suitable for all women with polycystic, while D-chiral inositol is only suitable for women with insulin resistance to polycystic, so the choice of which inositol is different from person to person. It is recommended that you first go to a regular hospital to confirm your diagnosis and ask your doctor to arrange for a glucose tolerance test OGTT and an insulin release test IRT.

If you are not insulin resistant, then Myo inositol alone is sufficient. If you are insulin resistant then D-chiral inositol or Myo inositol combined with D-chiral inositol is recommended.

There is now some new research that suggests that Myo inositol and D-chiral inositol work best when supplemented in a 40:1 mix. This theory is justified because, as mentioned earlier, the plasma Myo inositol to D-chiral inositol ratio in healthy women is exactly 40:1.

In clinical trials, the 40:1 formula has also proven its efficacy, but in the case of polycythemia vera, which varies greatly from person to person, we still need to analyse the evidence, as some people need more D-chiral inositol, and 10:1 or 4:1 is also good.

Cas No 643 12 9 D Chiro Inositol Powder For Food Supplement Products 1

Does Inositol have side effects?
For women with PCOS, Myo Inositol and DCI Inositol are the ones that work. From the medical evidence, no clinical trials available have found Myo Inositol to be toxic. This means that inositol is safer than fructose and salt.

Even in infants under 29 weeks, there were no adverse effects at a dose of 80mg/kg and even improvement in respiratory distress syndrome, and the Myo inositol in infant formula acts as a nutritional fortifier. In adults, there are also no serious adverse reactions to 30g of inositol per day, with the only mild reaction being gastrointestinal discomfort at doses greater than 12g. However, you need to understand that women with polycystic conditions only need 2-4g of Inositol per day to be effective and do not need 12g at all.

As for D-chiral inositol, some studies suggest that over 600mg may have a negative impact on oocyte quality in women with non-insulin resistant polycystic women and therefore D-chiral inositol should not be supplemented in excessive amounts.

The US FDA also considers inositol to be a natural substance that is generally recognized as safe.

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