Antioxidants Organic Kombu Extract Powder Ratio Extract

Product Description

Antioxidants Organic Kombu Extract Powder Ratio Extract

Product Introduction of Kombu Extract Powder
Kelp extract is made from the leafy body of Laminaria japonica Aresch and the contents are extracted by physical, chemical or biological techniques to break down the cell wall, rich in physiologically active substances such as seaweed polysaccharides (alginate), mannitol, amino acids, vitamins, minerals, phytohormones and betaine. Kombu Extract Powder has a variety of pharmacological effects such as antioxidant, anticoagulant, antitumour, antibacterial, hypoglycaemic and anti-radiation. It is widely used in food, medicine, textile and other industrial fields.

Kelp polyphenols are a class of potential marine natural antioxidants with strong antioxidant activity. The miraculous protective effect of seaweed extracted from kelp on living organisms is due to its ability to form a unique protective film on the cell surface under adverse environmental conditions such as high temperature, high temperature, high osmotic pressure and dry water loss, which effectively protects protein molecules from inactivation, thus maintaining the life processes and biological characteristics of living organisms. This unique functional property makes alginose not only an excellent active protective agent for protein drugs, enzymes, vaccines and other biological products, but also an important ingredient for maintaining cellular activity and moisturising cosmetics, and a unique food ingredient for preventing food deterioration, maintaining fresh food flavour and improving food quality, expanding the functions of it as a natural edible sweetening sugar.

Nutritional Components
Protein, carbohydrates, kelp polyphenols, fatty acids, fucoidan, alginic acid, mannitol, kelp polysaccharides, kelpamic acid, carotenoids, vitamins B1 and B2, vitamin C, proline, glutamic acid, aspartic acid, alginic acid, calcium, phosphorus, iron, iodine, potassium, cobalt, fluorine, etc.

Certificate of Analysis

Product Function of Kombu Extract Powder
1. Antioxidant effect
Studies have shown that the ethyl acetate extract of kelp has a higher capacity to scavenge a variety of free radicals than the antioxidant 2,6-di-tert-butyl, in a dose-dependent manner. Kelp polyphenols are the main components of the antioxidant activity in kelp, and kelp polysaccharides also have antioxidant activity.

2. Anti-tumour effects
Mice were gavaged with different doses of kelp polysaccharide, and the results showed that it could significantly enhance the proliferation of T lymphocytes in normal mice and immunosuppressed mice, and increase the activity of NK cells. Treatment of HeLa cells with different concentrations of kelp polysaccharide sulphate showed that it not only inhibited the growth of human cervical cancer cell lines, but also regulated the expression of bc-l2 protein and NF-JBp65 to affect the apoptosis of cervical cancer cells. When the anti-tumour activity of the crude extract of kelp polyphenols was measured by MTT method, it was found to have some inhibitory effect on A549, P388, BEL-7402, Hela and other cancer cells.

3. Antibacterial effect
Studies have shown that different solvent extracts of kelp extract powder have a more obvious inhibitory effect on Bacillus subtilis, Escherichia coli, Tetrahymena and Staphylococcus aureus, and still show some inhibition on the above species after dilution, among which the ethyl acetate extract has the most obvious inhibitory effect on Bacillus subtilis.

4. Hypoglycemic effect
Kelp polysaccharide can significantly reduce blood glucose and urea nitrogen in diabetic mice, increase serum calcium and serum insulin levels in diabetic mice, and have a significant restorative effect on islet damage caused by tetraoxine, it has a hypoglycemic and pancreatic islet cell protection function in diabetic mice.

5. Anti-radiation effect
Daily exposure to UV radiation decreased the malondialdehyde and hydrogen peroxide content of skin tissue and increased the levels of catalase, hydroxyproline, type I collagen mRNA, SO, glutathione peroxidase and serum NO in mice in the kelp polysaccharide high dose group. Meanwhile, ultramicroscopy showed that the MVEC cell membranes of this group of mice were intact and the mitochondrial cristae were clear. It showed that kelp polysaccharide could enhance the antioxidant capacity of the skin, regulate the synthesis of skin collagen and protect the skin MVEC cells.

6. Anti-fatigue and anti-hypoxia effects
The mice gavaged with kelp polysaccharide were subjected to 10 days of anti-fatigue and confined hypoxia tests. It was found that the survival time of the mice under weighted swimming and normoxia was significantly prolonged, and the haemoglobin content was significantly increased, indicating that kelp polysaccharide had better anti-hypoxic effect and anti-fatigue effect. The blood gas analysis of hypoxic mice again demonstrated that kelp polysaccharide could improve the utilization of oxygen in the tissues of hypoxic mice.

7. Immunomodulatory effects
Kelp rockulose sulphate has good immune activity and has a direct effect on T cells and macrophages, resulting in better immunomodulation in immunocompromised mice.

8. Anticoagulant and antithrombotic
The formation of kelp polysaccharides significantly prolonged the blood activated partial thromboplastin time (APTT), prothrombin time (PT) and whole blood clotting time (CT) in rabbits with a significant dose effect, indicating that kelp cell wall polysaccharides have some anticoagulant effect. The low molecular weight rockulose sulphate in kelp inhibited thrombus formation by inhibiting the tissue factor pathway of the exogenous coagulation pathway and hence thrombus formation. Comparison of the duration of total vascular obstruction revealed that the antithrombotic capacity increased with increasing molecular weight of alglucan sulphate.