Product Description
Procuct Information of Herbal Extract Powder
Name Kaempherol
Molecular weight 286.23
Molecular formula C15H10O6
Melting point 276°C-278°C
Solubility Slightly soluble in water, soluble in hot ethanol, ether and alkali.
Procuct Introduction of Herbal Extract Powder
Kaempferol has been identified as one of many flavonoids found in food, as with others such as lignans and quercetin. By itself, it shows promise as an anti-obesity agent and an anti-cancer agent.
Kaempferol, as a polyphenol, is present in many compounds. Common sources include:
Apples
Citris Fruits
Grapes and red wine
Onions and leeks
Tea (camellia sinensis)
Ginkgo Bilboa and St.Johns Wort
Nymphaea odorata
Alpinia officinarum hance, or Galangal Extract
Hedyotis verticillata (Source of kaempferitrin, kaempferol's rhamnoside sugar form)
Red beans and pinto beans (husk)[3] generally the species of bean Phaseolus Vulgaris.
Certificate of Analysis
| Product Name |
Kaempferol |
| Botanical Source |
Sophora Japonica L. |
| Plant Part Used |
Fruit |
| Quantity |
463kgs |
| Item |
Standard |
Test Result |
Test Method |
| Assay |
| Kaempferol |
≥98% |
99.32% |
HPLC |
| Physical&Chemical |
| Appearance |
Yellow fine Powder |
Complies |
Visual |
| Odor&Taste |
Characteristic |
Characteristic |
Organoleptic |
| Particle Size |
80mesh |
100% Pas 80mesh |
USP<786> |
| Ash |
≤2% |
0.82% |
USP<281> |
| Loss on Drying |
≤2% |
1.04% |
USP<731> |
| Heavy Metal |
| Pb |
≤1ppm |
0.45ppm |
ICP-MS |
| As |
≤1ppm |
0.62ppm |
ICP-MS |
| Cd |
≤1ppm |
0.13ppm |
ICP-MS |
| Hg |
≤0.5ppm |
0.005ppm |
ICP-MS |
| Microbiological Test |
| Total Plate Count |
≤1,000cfu/g |
Complies |
AOAC |
| Yeast&Mold |
≤100cfu/g |
Complies |
AOAC |
| E.Coli |
Negative |
Negative |
AOAC |
| Salmonella |
Negative |
Negative |
AOAC |
| Staphylococcus |
Negative |
Negative |
AOAC |
| Conclusion |
| Conform with specification, Non-GMO, Non-irradiation, Allergen, TSE/BSE Free. |
| Storage |
| Store in cool and dry places. Keep away from strong light and heat. |
| Packing |
| By 25kgs/Drum, inner by plastic bag or aluminum foil bag. |
| Shelf Life |
| 24 months under the above condition, and in it’s original package. |
Pharmacological action of Herbal Extract Powder
Glucose Uptake
Kaempferol, potentially through the metabolite kaempferol-3-neohesperidin, possibly increases glucose uptake by myocytes through processes mediated by the phosphatidylinositol 3-kinase (PI3K) and protein kinase C (PKC) pathways, and is suspected to be as effective as insulin in this regard.
Osteoblasts
Similar to myricetin, Kaempferol prevents against oxidation in in vitro bone cells and may exert anti-osteoporotic effects.
Adipogenesis
The inhibitory activity of kaempferol on fatty acid synthase (FASN) is achieved by acting as an inhibitor of the FASN cascade, which uses two substrates malonyl-CoA and acetyl-Coa together with NAPDH to ultimately produce palmitic acid.
Kaempferol (as well as quercetin) inhibits the activation of PPARγ lipogenesis by rosiglitazone and other endogenous ligands because of its high affinity for the receptor but low potency to activate it.
Kaempferol has long been known to reduce adipocyte formation, possibly by making its stem cells (bone marrow cells) favour osteogenesis (bone formation) over adipocyte formation.
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