Product Description
Product Introduction of Broccoli Sprout Extract Sulforaphane
Sulforaphane, which is abundant in cruciferous plants such as broccoli, kale and northern carrots, is a common antioxidant and the most potent and effective active ingredient among natural anti-cancer substances. It is a multifunctional inducer that induces the production of type II detoxifying enzymes, glutathione transferase and quinone reductase, which are resistant to many carcinogens and prevent carcinogens from destroying genetic factors in healthy cells, thus acting as an anti-cancer agent.
The Discovery of Broccoli Sprout Extract Sulforaphane
In 1992, Talalay's laboratory announced the discovery of a super-powerful substance that induces phase2 enzymes, called Sulforaphane, a chemical extracted from cauliflower that has anti-cancer properties. He then carried out research on Sulforaphane, using rats exposed to the carcinogenic substance as subjects. The results were truly astonishing. The number of rats that had breast tumours was reduced by 60% in the rats that received Sulforaphane. What's more, in the case of the rats with cancer, the size of the tumours was reduced by 75 per cent. In view of the above, it is of great significance to develop and produce health food products by extracting or chemically synthesising Sulforaphane from the cruciferous plant. Japanese nutritionist Professor Yoko Fukuya and others have verified through tests that Sulforaphane, an isothiocyanate derivative contained in cruciferous plants such as kale and cauliflower, has the ability to treat cancer and kill leukaemia cells, the first time it has been confirmed to have the ability to kill leukaemia cells.
Anticancer Effects of Broccoli Sprout Extract Sulforaphane
Sulforaphane is a multifunctional enzyme inducer that induces the body to produce a type II detoxifying enzyme, glutathione transferase (GST) and quinone reductase (QR), which neutralise suspected carcinogens and prevent them from damaging genetic factors in healthy cells, thus acting as an anti-cancer agent.
Sulforaphane is only one of many isothiocyanate derivatives with anticancer activity. An isothiocyanate compound, either natural or synthetic, has been found to directly inhibit both the methylation of CpGDNA in the gene promoter/5-UTR region and the activity of histonedeacethylases (HADC), which selectively promotes histone acetylation and methylation, thereby restoring the expression of some functionally important genes in cancer cells and bringing their normal function under control. It also directly inhibits the activity of histonedeacethylases (HADC), which selectively promotes histone acetylation and methylation, thereby restoring the expression of some functionally important genes that have been abnormally shut down in cancer cells and enabling the malignant proliferation of cancer cells to be controlled, thus effectively inhibiting the growth of human tumour cells, including colon, stomach, lung, prostate, liver, colon, melanoma and neuroblastoma.
Compared to known DNA methylation inhibitors and natural or synthetic histone deacetylase inhibitors, these compounds are unique dual inhibitors with strong anti-cancer effects, low toxicity and stable biological properties for the treatment and prevention of various malignancies.
Researchers at the UK Food Research Agency believe that Sulforaphane can stimulate the body's self-fighting mechanisms against cancer. Evidence shows that Sulforaphane can help antioxidants maintain the body's health balance when environmental, food and other carcinogenic substances are affecting the body. This is because Sulforaphane activates a gene in the body that increases antioxidant levels and produces the HDAC enzyme that stops tumour growth. At the same time, Sulforaphane also promotes the body's production of enzymes that have an excretory effect on carcinogens. When people eat broccoli, they produce Sulforaphane as a result of ingesting the element glycoside. Researchers at the UK Food Research Agency believe that Sulforaphane can stimulate the body's self-fighting mechanism against cancer. Sulforaphane activates a body gene that boosts levels of antioxidants and blocks an enzyme that can promote tumour growth. The research suggests that Sulforaphane may stop the development of cancer stem cells, while chemotherapy and radiation therapy may cause a rebound in the growth of that cancer cell.
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