Product Description

Product introduction

Vitamin K2 MK-7 Powder belongs to the Vinoxol K group. The vitamin K group consists of vitamin K1(chloroquinone) found in green leafy vegetables, which makes up the vitamin in a typical Western dietAbout 90% of K; Also included is vitamin K2, which is made up of different methylnaphthalases and makes up about 10 percent of the Western diet. Methyl naphthalene is commonly found in fermented foodsProducts such as cheese, yoghurt and tofu are least synthesized in our bodies by the gut microbiome, unlike those made by a variable number of unsaturated isoprene residues Its constituent side chain, methyl naphthalene, is named MK-N, where n specifies the number of isoprene like chains. Variations in length give it different utilization rates and workEffect. Vitamin K2 MK-7 Powder, with its seven isoprene units, is well studied and has been shown to have higher bioavailability and efficacy than dry vitamin K1 and vinoxin K2(MK4).

Vitamin K2 MK-7 Powderwas first isolated from natto, a traditional Japanese food made from beans fermented with a specific bacterium, Bacillus subtilis natto. Several studies have linked natto intake and its high levels of MK7(1000ug/100g) to improved bone health and reduced cardiovascular risk factors.Bacillus subtilis natto only produces Vitamin K2 MK-7 Powder with the trans structure, where the "trans" represents the double bond spatial configuration of the isoprenoid side chain. This all-trans structure is unique to all xanthopancreas and enables it to play a key role in the electron transport chain (respiratory chain) of prokaryotes as an electron permeable protein in the plasma membrane, possessing antioxidant properties that protect the membrane from lipid oxidation. In humans, the biological activity of MK7 is closely related to its natural all-trans structure. The cis-analogue of vitamin K2 is inactive

Fancution

Vitamin K2 MK-7 Powder has been shown to promote bone health and help prevent cardiovascular disease in humans, with the quality of the bacillus subtilis natto fermentation determining efficacy.A meta-analysis published in 2015 assessed the role of Vitamin K2 MK-7 Powder in the prevention and treatment of osteoporosis in postmenopausal women, including 19 randomized controlled trials, which showed significant improvement in vertebral bone mineral density in the vitamin K2 treatment group, both in the medium and long term. A recent study by Knapen et al. reported the results of arterial wall thickening and hardening in a cohort of healthy postmenopausal women treated with MK7 over a period of three years (180 MCG/day).

Women in the MK7-treated group had a significant reduction in atherosclerosis compared with placebo, especially among subjects with high baseline arterial stiffness. Active VitaMK7 has been studied in published preclinical and clinical studies. Specifically, based on data from Natto derived MK7, VitaMK7 was tested in a single dose (a 1 mg fat breakfast) trial in healthy volunteers and showed a typical MK7 bioavailability pattern. The highest dose dissolved in olive oil and Vitamin K2 MK-7 Powder at 45 or 90 μ g/day for two weeks significantly improved osteocalcin carboxylation

Application

Due toVitamin K2 MK-7 Powderexcellent stability (stored at room temperature for up to 3 years), VitaMK7 can be used in a wide range of formulations, such as tablets. Capsules, soft gels and powders. Due to its high purity, VitaMK7 is also stable when formulated with a variety of calcium salts, such as carbonate and limate, and has been proven to be suitable in liquid preparations such as water, yogurt and oils.