C28H38N6O11S Sildenafil Citrate Powder Viagra Pill Powder For Erectile Dysfunction

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Introduction:

best sildenafil is a drug used to improve male sexual dysfunction. This drug acts on phosphodiesterase and is an inhibitor of phosphodiesterase. Generally, when encountering sexual stimulation, it can stimulate the release of local nitric oxide. Sildenafil can increase the guanylate cyclase in the cavernous body by inhibiting phosphodiesterase, relax the smooth muscle of the cavernous body, so that blood enters the cavernous body. Play a therapeutic effect to improve erectile dysfunction of the penis.

Product Description:

CAS: 139755-83-2

Apperance :White Crystalline Powder

MF :C22H30N6O4S

MW :474.58

Shelf Life :24 Months

COA

Function:

best sildenafil Viagra.It is a V-phosphodiesterase inhibitor, used to treat erectile dysfunction.

Application

best sildenafil is a drug used to improve male sexual dysfunction. This drug acts on phosphodiesterase and is an inhibitor of phosphodiesterase. Generally, when encountering sexual stimulation, it can stimulate the release of local nitric oxide. Sildenafil can increase the guanylate cyclase in the cavernous body by inhibiting phosphodiesterase, relax the smooth muscle of the cavernous body, so that blood enters the cavernous body. Play a therapeutic effect to improve erectile dysfunction of the penis.

Other influence

BoolellM et al. conducted a study on a group of healthy volunteers, with doses ranging from 1.25 mg to 200 mg. Take it once a day, check the heart rate and blood pressure before and after taking the medicine, and keep blood and urine samples for analysis. the result shows:
1. Sildenafen is quickly absorbed by oral administration, and the plasma drug concentration reaches its peak within 1 hour after taking it;
2. The half-life of the drug is short, about 3-5 hours, and there is no obvious drug accumulation in one dose per day;
3. Using different doses from 1.25mg to 200mg, the average maximum plasma concentration and the area under the concentration-time curve will increase proportionally with the increase in the dose;
4. The average hourly plasma clearance rate is 41/L, the average stable volume of distribution is 105/L, and the average effective bioavailability of taking 50 mg sildenafil is 41%;
5. No obvious effect on blood pressure and heart rate