Le Nutra Natural Fisetin Powder

Le-Nutra Natural fisetin powder fisetin 98% smooke tree extract powder anti-aging Herbal Extract Powder

Base information of Product

COA of Product

Introduction of Product

Fisetin is a kind of flavonoids, poorly soluble in water, carbon tetrachloride, and petroleum ether, soluble in acetone, acetic acid, such as solvent, widely exists in the strawberry, apple, onion, cucumber and other fruits and vegetables, the source is extensive, cheap, has extensive pharmacological activities, such as anti-inflammatory, antioxidant, anticoagulant, antithrombotic, spasmolysis, diabetes, kidney damage, etc. In recent years, Fisetin has been found that lushanthin can play an anti-tumor role by inhibiting tumor cell proliferation, signal transduction pathway and inducing tumor cell apoptosis. Therefore, lushanthin has attracted increasing attention. However, it is difficult to dissolve in water and has low bioavailability, which limits its further development and clinical application. At present, the research of fisetin is focused on the pharmacological activity, mechanism of action, extraction technology and so on, and there are few reports on related dosage forms.

In recent years, the researchers try to paint flavin liposomes and nano micelle preparation to improve its solubility, to improve the bioavailability and antitumor effects, such as liposome preparation paint flavin, after intraperitoneal injection of drug delivery can obviously improve the solubility and bioavailability, and when a tumor-burdened antitumor activity in mice experiments found that compared with active pharmaceutical ingredients, Low dose liposomes can significantly increase the anti-tumor effect. Preparation of fisetin micelles can increase its solubility and anti-tumor effect.

Function of Product

1. Fisetin has pharmacological characteristics of anti-oxidation, anti-inflammation and neuroprotection, and can play an anti-tumor role by inducing apoptosis of tumor cells, affecting signal transduction pathways of tumor cells, inhibiting proliferation of tumor cells, and inhibiting migration and invasion of tumor cells.

2. Studies have shown that fisetin also exudes antidepressant effects by inhibiting serotonin and monoamine oxidase in the norepinephrine system. It can protect and repair liver injury caused by hepatitis. It can significantly improve the activity of immune cells. As reported in the Proceedings of the National Academy of Sciences, lushanthin stimulates signaling pathways that improve long-term memory. It also inhibits the cytotoxicity of aflatoxin.

Application of Product

Fisetin has been found that lushanthin can play an anti-tumor role by inhibiting tumor cell proliferation, signal transduction pathway and inducing tumor cell apoptosis. Therefore, lushanthin has attracted increasing attention. However, it is difficult to dissolve in water and has low bioavailability, which limits its further development and clinical application.