Acesulfame K Potassium Sweetener

 
Le-Nutra Acesulfame K potassium acetylsulfonate sweetener Nutritional Food Additive Powder
 
 
Base information of Product
 
 

 
 
 
History of Product
 
Acesulfame K was invented by Karl Krauss in Germany in 1967. The World Health Organization approved the use of its generic name (acesultar) as a low-calorie sweetener in 1978. It is 200-250 times sweeter than sucrose. Acesulfame K is stable to light and heat (225℃ high temperature) and has a wide range of pH values (pH=3-7). It is one of the most stable sweeteners in the world. It does not absorb moisture in the air and does not react with other food ingredients or additives when used. Suitable for baked goods and sour drinks. In addition, the safety of Acesulfame K is high. The joint FAO/WHO Expert Committee on Food Additives has approved the use of acesulfhoney as A grade A food additive, and the recommended average daily intake (ADI) is 0-15mg/kg. In 1988, the United States Food and Drug Administration (FDA) approved the use of acesulfamil in food with a prescribed daily intake (ADI) of 0-15mg/kg. In 1998, the FDA approved acesulfamil in soft drinks. The sweetness of acesame is pure and strong, better than that of sucrose. The sweetness lasts for a long time, and the combination of aspartame and aspartame has obvious synergistic effect by 1:1.
 

Function and Appication of Product
 
1. Acesulfame K is considered one of the most promising sweeteners because of its uncomplicated production process, low price and superior performance to aspartame. After 15 years of experiments and tests, the United Nations World Health Organization, the United States Food and Drug Administration, the European Community and other authoritative organizations have concluded that "acesultar is safe and harmless to human and animals". At present, there are more than 90 countries around the world officially approved acesultar for food, beverage, oral hygiene, cosmetics (can be used in lipstick, lipstick, toothpaste and mouthwash, etc.) and pharmaceutical (used in syrup preparation, sugar-coated tablets, bitter medicine masking agent, etc.) and other fields.
 

 
2. As a non-nutritive sweetener, Acesulfame K has almost no change in its concentration when used in food and beverage within the general pH range. It can be used in combination with other sweeteners, especially aspartame and cyclohexyl sulfonate. Can be widely used in solid drinks, pickles, preserves, gum sugar, table sweeteners of all kinds of food. The product has a strong sweet taste, about 200 times as sweet as sucrose, taste similar to saccharin, high concentration has a bitter taste.
 

 
 
 
 

The preparation methods

 
1. Acetyl acetamide, sulfur trioxide and KOH as raw materials
 
The first is the synthesis of acetylacetaminosulfonic acid in an inert organic to inorganic solvent, so that SO3 is passed into acetylacetamide for cyclic condensation. Then it is extracted and separated, and then reacted with KOH to get the product. For example, 5.1g (50mmol) acetylacetamide dissolved in 50mL CH2Cl2 was dropped into 8mL (200mmol) liquid SO3 dissolved in 50mL CH2Cl2 at -60 ° C. After stirring for 2h, 50mL ethyl acetate and 50mL water were added to the solution. The organic phase was separated after extraction. The aqueous phase was extracted twice by ethyl acetate and the organic solution was incorporated into the organic phase. The ethyl acetate was recovered by evaporation after drying on anhydrous Na2SO4. The residue was dissolved in methanol and neutralized with KOH solution to precipitate Acesulfame K. after drying, 3.1g product was obtained with a recovery rate of 31% of the theoretical amount. The disadvantage of this method is that the reaction should be carried out at a relatively low temperature and the yield is not high. 
 
2. With amino sulfonic acid, triethylamine, dienone, SO3 and KOH as raw materials
Add 9.7g (0.1mol) sulfamic acid to 16mL (0.12mol) triethylamine, stir until completely dissolved, then drop 8mL dienone at 0℃, stir until the end of the reaction at room temperature. Hexane is added to precipitate and refine the precipitate. When the solvent is removed under reduced pressure, a slurry is obtained with yields ranging from 95.7 to 99.0%. At -30℃, the slurry was added to a container containing CH2Cl2 with 5-6 equivalent at the same time for continuous stirring for 1-5h. The solvent was removed by decompression, the remaining KOH solution was treated at pH=8-10, and the solvent was desiccated and dried to obtain Acesulfame K with a yield of 69%. The advantage of this method is that the raw material is easy to obtain, the technological condition is mild, but the procedure is complicated. 
 
3. Aminosulfonyl fluoride, dienone, potassium carbonate and KOH are used as raw materials
At 0℃, dienone is dropped into the acetone solution of H2NSO2F and K2CO3 to prepare the potassium salt of acetophenol hexophthalamine -N-sulfophthalfluorine, which is reacted with the solution of CH3OH and KOH to prepare acesulfamil. For example, 76g (0.55mol) K2CO3 powder is dissolved in 500mL acetone, 57.8mL (1.0mol) H2NSO2F is added, 84.3mL (1.1mol) dienone is added within 15 minutes, and the mixture is stirred at 0℃ for 30 minutes, then exothermic reaction occurs, and the temperature is controlled below 30℃. The reaction can be stopped until the CO2 is completely released. The reaction mixture was filtered and washed with a small amount of acetone. The result is a colorless crystalline potassium salt of acetylacetamide -N- sulfonphthalafluorine. The potassium salt is stirred with 4-6mol of methanol solution to cyclamate into Acesulfame K. The yield is 93% of the theoretical amount.